Publication
Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples
Eli Fenichel and 15 other contributors
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APR
Citation
Watkins, A. ., Fenichel, E. ., Weinberger, D. ., Vogels, C. ., Brackney, D. ., Casanovas-Massana, A. ., … Wyllie, A. . (2021). Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples. EMERGING INFECTIOUS DISEASES, 27(4), 1184-1187. https://doi.org/10.3201/eid2704.204200 (Original work published 2024)
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Abstract
We analyzed feasibility of pooling saliva samples for severe acute respiratory syndrome coronavirus 2 testing and found that sensitivity decreased according to pool size: 5 samples/pool, 7.4% reduction; 10 samples/pool, 11.1%; and 20 samples/pool, 14.8%. When virus prevalence is >2.6%, pools of 5 require fewer tests; when <0.6%, pools of 20 support screening strategies.